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Drug Excretion: Pulmonary and Glandular Routes in Pharmacokinetics and Pharmacodynamics | JoVE Core
The mechanism of action of ARQ172 is associated with a futile redox cycle in NQO1+ cancer cells, where NQO1 reduces ARQ 761 to an unstable hydroquinone, which is autoxidized to quinone, generating O 2 and H 2 O 2 in the process
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