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[Google Scholar] Aggarwal BB, Gehlot P

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This metabolic process, which requires oxygen consumption, contributes to the establishment of anaerobic conditions in the colonic lumen and results in the stabilization of hypoxia-inducible factor-1 (HIF-1) in colonocytes ( Cldn1 (encoding Claudin-1) and Ocln (encoding occludin) in a HIF-1-dependent manner, thereby conferring resistance to barrier disruption and bacterial translocation upon infection with Clostridium difficile ( Microbial indoles also regulate the integrity of TJs