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Intracellular detoxification of the p450 and glutathione pathway | Download Scientific Diagram
Within the lung tumor microenvironment, CPT1A—a master regulator of fatty acid β-oxidation—cooperates with macrophage-derived L-carnitine to orchestrate a dual outcome: conferring resistance to ferroptosis while simultaneously impairing the antitumor function of CD8 + T lymphocytes (38)
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This indicates that lipid desaturation could serve as a potential biomarker for identifying OCSCs (93)
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