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The same effects were observed when U2OS cells transduced with HRASV12 or cyclin E1 retroviruses were treated with the RNAPII transcription initiation inhibitor triptolide (TRP) for one hour prior to and during pulse labeling with CldU and IdU (Fig

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However, a subgroup of children with a non-verbal IQ above 70 showed notable improvements in communication skills, sustained attention, and brain activity, suggesting that stem cell therapy may be more effective for children with higher cognitive function