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As a result of SAR studies and computational optimization, this group developed PROTAC 93 capable of inducing the degradation of the BTK C481S mutant protein (DC 50 = 3.8 nM), with a DC 50 approximately five times higher than that of the first-generation BTK degrader P13I
Anti-Inflammatory Support
Flavour:Orange 30 Tabs
Adenosine and Inflammation: Here, There and Everywhere
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US$40
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