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In the Wnt pathway, the key step of the Wnt pathway is the binding of the Wnt protein to the Frizzled receptor, and the nuclear redox protein (NRX) blocks Disheveled (DVL) and plays a negative regulatory role in the Wnt pathway (Yu et al., 2021)

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Therefore, the results of this study could provide valuable new opportunities for mushroom growers, since mushrooms can serve as an excellent source of antioxidants, specifically ERG, and provide new potential for commercial scale production of ERG through large-scale bioreactors