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733 PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES › VASOPRESSIN AND ANALOGUES Terlipressin acetate l 22-Apr-2021 INDICATIONS AND DOSE GLYPRESSIN ® INJECTION Bleeding from oesophageal varices ▶ BY INTRAVENOUS INJECTION ▶ ▶ Adult (body-weight up to 50 kg): Initially 2 mg every 4 hours until bleeding controlled, then reduced to 1 mg every 4 hours if required, maximum duration 48 hours Adult (body-weight 50 kg and above): Initially 2 mg every 4 hours until bleeding controlled, reduced if not tolerated to 1 mg every 4 hours, maximum duration 48 hours VARIQUEL ® INJECTION Bleeding from oesophageal varices ▶ BY INTRAVENOUS INJECTION ▶ ▶ ▶ ▶ Glypressin (Ferring Pharmaceuticals Ltd) Terlipressin acetate 120 microgram per 1 ml Glypressin 1mg/8.5ml solution for injection ampoules | 5 ampoule P s (Hospital only) Variquel (Alliance Pharmaceuticals Ltd) Terlipressin acetate 200 microgram per 1 ml Variquel 1mg/5ml solution for injection vials | 5 vial P £89.98 (Hospital only) Adult (body-weight up to 50 kg): Initially 1 mg, then 1 mg every 4–6 hours for up to 72 hours, to be administered over 1 minute Adult (body-weight 50–69 kg): Initially 1.5 mg, then 1 mg every 4–6 hours for up to 72 hours, to be administered over 1 minute Adult (body-weight 70 kg and above): Initially 2 mg, then 1 mg every 4–6 hours for up to 72 hours, to be administered over 1 minute Obesity Obesity 01-Jun-2016 Description of condition Obesity is directly linked to many health problems including cardiovascular disease, type 2 diabetes, fatty liver disease, gallstones, and gastro-oesophageal reflux disease

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Published 2013 Sep 30