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Abstracts - PMC
Research suggests that arsenic trioxide, used in the treatment of acute promyelocytic leukemia, induces apoptosis and generates reactive oxygen species (ROS) as part of its mechanism of action (Murillo et al., 2022
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Further, activation of the AT 1 receptor results in the stimulation of the NF-kB signal transduction pathway facilitating the synthesis of chemokine, cytokines, and adhesion molecules, all important in the migration of inflammatory cells into regions of tissue injury (107)
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