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In summary, the key findings from these recent GHSR 1a structures support the following (as depicted in Figure 4): Key Findings from Recent Structural Studies Signaling is initiated by pronounced conformational changes in TMVI, TMVII, and ECL2

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Methylation arrays (e.g., Infinium 450K/850K) Methylation arrays are high-throughput tools for analyzing DNA methylation across the genome, including CpG islands, promoters, and enhancers (57, 58)