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The following three enzymes play a major role in the repair of proteins with oxidative damage: GSH–Dependent Thioltransferase (TTase) or Glutaredoxin (GRx) This is a member of the thiol-disulfide oxidoreductase enzyme family with two isozymes: cytosolic TTase-1 (GRx1) and mitochondrial TTase-2 (Grx2) [145, 146]
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