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Even though GSTs can act on hundreds of electrophilic compounds ( trans -2-nonenal representing reactive α,β-unsaturated aldehydes formed by lipid peroxidation (Figure 5 shows stacked specific activities with these substrates combined with the specific activity with 5-AD
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However, translation to therapeutic applications requires completion of Phase III clinical programs with defined primary endpoints
Carnitine assists in the processing of fatty acids
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