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Collectively, these findings indicate that enhanced glutamine metabolism and cell growth dysregulation are established in K-Ras-driven cancer cells to promote uncontrolled cell growth and to assist with glutamine acquisition and utilization for cell growth

gluta-C

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Thirdly, GPX4 levels decreased in cartilage from the OA animal models, and knockout of GPX4 exacerbated mice experimental OA process [111]