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Mitochondrion-targeted carboxymethyl chitosan hybrid nanoparticles loaded with Coenzyme Q10 protect cardiac grafts against cold ischaemia‒reperfusion injury in heart transplantation | Journal of Translational Medicine | Springer Nature Link
This activation initially protects the brain cells, but can aggravate inflammation by the release of more cytokines, ROS, and excitotoxic glutamate
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Huang H, Tohme S, Al-Khafaji AB, Tai S, Loughran P, Chen L, et al
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