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The aim of this paper is to analyze the protein structure and biological function of GPx4, to systematically explore the core regulatory role of this enzyme in the ferroptosis pathway and its molecular mechanism in various diseases, and ultimately to break through the existing therapeutic bottlenecks based on the current progress of research, and to provide a new idea for the precise intervention strategy targeting GPx4
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J Alzheimers Dis 17: 661–680, 2009
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