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However, NH 3 can cross cell membranes, allowing, for example, NH 3 to pass into the urine from kidney tubule cells to decrease the acidity of the urine by binding protons to form ammonium ions (NH 4 + )

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The phenolic OH and CH 2 groups in the β-diketone moiety of these compounds confer anti-inflammatory and antioxidant properties, among other bioactivities, making curcumin a valuable nutraceutical for chemo-preventive and therapeutic applications (23, 43)