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Via the integration of GST inhibitor screening, enzyme inhibition kinetics, and molecular modeling approaches, they identified that 2,2′-dihydroxybenzophenones 6 and 8, as well as the N-acyl hydrazone analogues 14 and 16, exhibited satisfactory inhibitory potencies (IC 50(6) = 1.77 ± 0.10 μM

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Symptoms of endometriosis can include: Severe menstrual cramps Increased menstrual bleeding Painful bowel movements Painful intercourse Abdominal Pain Infertility The cause of endometriosis isn’t fully understood but involves inflammation, altered immunity, genetics, environmental toxins, and excess estrogen