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The Rockefeller University » Lack of a single molecule may indicate severe and treatment-resistant depression

Although certain studies have limitations, either in the design or number of participants, the majority point to an association between symptoms and DAO deficiency, establishing a general trend that supports the key role of DAO in the etiology of these disorders

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The authors of this work, in previous studies, have applied a systems biology approach to develop a methodology that enables the identification, aggregation, and integration of the signaling cascades at the cellular level to develop molecular systems architectures