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The peptide boom: why everyone's suddenly talking about BPC-157, its bold claims - and the hidden risks | Men's Fitness

Abbreviations Used 3ClY 3-chlorotyrosine 3NY 3-nitrotyrosine ABCA1 ATP-binding cassette transporter A1 AD Alzheimer's disease ALS amyotrophic lateral sclerosis apoAI apolipoprotein A-I DiClY 3,5-dichlorotyrosine DiY 3,3′-dityrosine DOPA 3,4-dihydroxyphenylalanine DQ dopaquinone EPO eosinophil peroxidase FeSOD iron superoxide dismutase GAPDH glyceraldehyde-3-phosphate dehydrogenase HDL high-density lipoprotein HOBr hypobromous acid HOCl hypochlorous acid HPLC high-performance liquid chromatography HPLC-MS/MS high-performance liquid chromatography-tandem mass spectrometry MnSOD manganese superoxide dismutase MPO myeloperoxidase m -Tyr meta -tyrosine, 3-hydroxyphenylalanine NO nitric oxide • NO 2 nitrogen dioxide o -Tyr ortho -tyrosine, 2-hydroxyphenylalanine ONOO − peroxynitrite PD Parkinson's disease PTM post-translational modification ROS reactive oxygen species SDS-PAGE sodium dodecyl sulfate polyacrylamide gel electrophoresis TPO thyroid peroxidase Acknowledgments We gratefully acknowledge support by the NIH (AG12993, AG23551, AG25350), the Madison and Lila Self Graduate Fellowship program at The University of Kansas, Amgen, and the Department of Pharmaceutical Chemistry at The University of Kansas

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Expression of growth hormone gene in the baboon eye