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359 In contrast, trehalose activates TFEB indirectly in neurons by inducing lysosomal membrane permeabilization and stimulating the calcium-dependent phosphatase PPP3/calcineurin, which dephosphorylates TFEB and promotes its nuclear translocation, increasing ATG expression and protecting against protein aggregation in neurodegeneration
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Size:180 Veg Capsules
78% were White, 16% were Asian, 2.9% were Hispanic or Latino, 2.1% were Black or African American, and 80 mL/min)
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