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For example, numerous studies have investigated how various neurotransmitter receptors and other activity-related mediators influence myelin, but in all cases where changes to myelin are observed upon manipulation of activity, earlier stages of oligodendrocyte lineage progression are also altered (for example 8,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36 )

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The expression of CAT was significantly increased after ALA supplementation both in the hypothalamus and the cerebral cortex when compared to the control (+98% and +77%, respectively) and to the HFD animals (+60% and +35%) (Figure 9)