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Even though severe magnesium deficiency has been unequivocally linked to muscle cramping, as magnesium is believed to mitigate muscular excitability, studies found no correlation between serum magnesium levels and the occurrence of muscle cramps in patients with cirrhosis (25, 28)
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Future studies are needed firstly to clarify a potential catalytic mechanism and secondly whether SnCE1 is able to acetylate protein substrates in trans similar to that described for ChlaDUB1 58
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