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Orexin-A may also raise blood glucose levels by sensing when blood glucose levels fall and modulating β-cell hormone secretion to maintain circulating glucose levels during fasting [171]

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On rare occasions, autonomic symptoms including blurred vision, hearing problems, memory loss, constipation, dizziness with positional changes, poor urinary functions, and reduced sexual performance, may also occur in CIPN patients (Mols et al., 2016