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Long-term pioglitazone treatment for patients with nonalcoholic steatohepatitis and prediabetes or type 2 diabetes mellitus: a randomized trial
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The strongest, clearest evidence is biochemical: growth hormone releasing compounds like CJC-1295 raise growth hormone and IGF-1, and studies of growth hormone secretagogues confirm they can increase IGF-1, a measurable marker on the pathway (a 2017 study showing a growth hormone secretagogue raised serum IGF-1, published in American Journal of Men’s Health in 2017)
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