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Early-phase clinical trials of potential drugs (MCC950, antler peptides, puerarin, necrostatin-1, and FGF23 inhibitors) in flexible, biomarker-guided designs will help speed up decisions about whether to move further or not
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CI values for the four primary AML patient samples ranged from 0.021 to 1 ( Supplementary Figures S3A-D ), among those doses two were reproduced in all four samples ( Figure 5B ), indicating a synergistic inhibition of AML cell growth with the combination of BI4916 and Rylaze
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