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We next assessed the production of other components of the coagulation machinery, including AT, which is one of the most potent anticoagulant proteins that inhibits multiple coagulation serine proteases, mainly thrombin (FIIa) and activated factor X (FXa) but also FVIIa, FIXa, FXIa and FXIIa

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They sit in a more uncomfortable middle ground: interesting biology, intriguing findings in animal studies, and, realistically, no convincing proof that they promote musculoskeletal healing in people